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Dr Chaaya Iyengar

vidwan id: 49001
Female

Assistant Professor, Department of Biotechnology
National Institute of Pharmaceutical Education and Research (NIPER), Mohali

Expertise

  • Biology

Publications

Total Articles 50
Books 0
Proceedings 0

Publications

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Scopus

Citations 889
h-index 14

CrossRef

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Citations 622
h-index 14
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Professional Recognition

2014

National Women Bioscientist Award (Young Category)

Department of Biotechnology

Community & Membership

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Bio

Host pathogen interaction, tuberculosis, multifunctional proteins, iron transport, protein expression and enzyme characterization in Mycobacterium tuberculosis are subareas of research. Recently we have identified a novel mechanism by which M.tb acquires transferrin iron in order to survive during infection. The findings were published in Nature Communication in August 2014. Other research is focused on identifying new drug targets and developing protein expression strategies.

Personal Details

  • Female
  • Assistant Professor , National Institute of Pharmaceutical Education and Research (NIPER), Mohali
  • National Institute of Pharmaceutical Education and Research, SAS Nagar, Mohali
Ph.D
Other Institute 2001
Assistant Professor Jun 2008 – Present
National Institute of Pharmaceutical Education and Research (NIPER), Mohali | Department of Biotechnology

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Dr Joydev K Laha

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Dr Chaaya Iyengar

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Co-Authors (8)

Arunava

Dr Arunava Dasgupta

Central Drug Research Institute

Avishek

Dr Avishek Saha

CSIR National Chemical Laboratory

Avishek

Dr Avishek Saha

Central Scientific Instruments Organization

Pravinkumar

Dr Pravinkumar Patil

Shivaji University

Prabha

Prof Prabha Garg

National Institute of Pharmaceutical Education and Research (NIPER), Mohali

Sidharth

Dr Sidharth Chopra

Central Drug Research Institute

Scholarly Work

The relevance of host and Mycobacterial GAPDH during infection”

Funding Agency: Department of Science and Technology, Govt. of India

NA

38.1 lakhs

2013 - 2016

Completed
Role of Mycobacterial GAPDH in Iron uptake

Funding Agency: Department of Biotechnology

NA

52.49 lakhs

2010 - 2014

Completed
Role of GAPDH as a multifunctional protein in Dendritic cells

Funding Agency: Department of Science and Technology Women’s Scientist Scheme (A)

NA

16.0 lakhs

2006 - 2009

Completed

Characterization of Mycobacterium tuberculosis H37Rv Glyceraldehyde-3-phosphate dehydrogenase (GAPDH, Rv1436) and its role in transferrin iron acquisition

University NIPER, SAS Nagar
Year 2016
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Scholarly Publications

Metformin induces iron deprivation and enhances mitochondrial ROS in macrophages creating a hostile environment for survival of intracellular Mycobacterium tuberculosis

Open Access
Article
Authors: Modanwal R.;Chaubey G.K.;Dilawari R.;Talukdar S.;Sindhu A.;Raje C.I.;Raje M.

Antimicrobial peptides: An alternative strategy to combat antimicrobial resistance

Open Access
Review

Chronic hyperglycemia impairs anti-microbial function of macrophages in response to Mycobacterium tuberculosis infection

Open Access
Article
Authors: Chaubey G.K.;Modanwal R.;Dilawari R.;Talukdar S.;Dhiman A.;Chaudhary S.;Patidar A.;Raje C.I.;Raje M.

Stoichiometry of ligand binding and role of C-terminal lysines in Mycobacterium tuberculosis and human GAPDH multifunctionality

Open Access
Article
Authors: Kumar A.;Kumar R.;Boradia V.M.;Malhotra H.;Kumar A.;Seth S.;Garg P.;Karthikeyan S.;Raje M.;Iyengar Raje C.

Mycobacterium tuberculosis exploits SIRT2 to trap iron for its intracellular survival

Open Access
Article
Authors: Talukdar S.;Modanwal R.;Chaubey G.K.;Dhiman A.;Dilawari R.;Raje C.I.;Raje M.

Glyceraldehyde-3-Phosphate Dehydrogenase Binds with Spike Protein and Inhibits the Entry of SARS-CoV-2 into Host Cells

Open Access
Article
Authors: Dilawari R.;Chaubey G.K.;Modanwal R.;Dhiman A.;Talukdar S.;Kumar A.;Raje C.I.;Raje M.

Unlocking translational machinery for antitubercular drug development

Open Access
Short Survey

Regulation of Macrophage Cell Surface GAPDH Alters LL-37 Internalization and Downstream Effects in the Cell

Open Access
Article
Authors: Dhiman A.;Talukdar S.;Chaubey G.K.;Dilawari R.;Modanwal R.;Chaudhary S.;Patidar A.;Boradia V.M.;Kumbhar P.;Raje C.I.;Raje M.