Dr Chaaya Iyengar

Female

Assistant Professor, Department of Biotechnology
National Institute of Pharmaceutical Education and Research (NIPER), Mohali

16199979800

Expertise

Biology

Publications

Total Articles 50

Books 0

Proceedings 0

Publications

Scopus

Citations 889

h-index 14

CrossRef

Citations 622

h-index 14

Google Scholar

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Professional Recognition

2014

National Women Bioscientist Award (Young Category)

Department of Biotechnology

Community & Membership

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Bio

Host pathogen interaction, tuberculosis, multifunctional proteins, iron transport, protein expression and enzyme characterization in Mycobacterium tuberculosis are subareas of research. Recently we have identified a novel mechanism by which M.tb acquires transferrin iron in order to survive during infection. The findings were published in Nature Communication in August 2014. Other research is focused on identifying new drug targets and developing protein expression strategies.

Personal Details

Female
Assistant Professor , National Institute of Pharmaceutical Education and Research (NIPER), Mohali
National Institute of Pharmaceutical Education and Research, SAS Nagar, Mohali

Ph.D

Other Institute 2001

Assistant Professor Jun 2008 – Present

National Institute of Pharmaceutical Education and Research (NIPER), Mohali | Department of Biotechnology

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Organisations (30+)

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Prof Arvind Kumar Bansal

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Prof Anand Sharma

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Dr Anil Kumar Angrish

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Dr Abhay Hariram Pande

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Prof Asit Kumar Chakraborti

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Assistant Professor

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Associate Professor

Assistant Professor

Co-Authors (8)

Dr Arunava Dasgupta

Central Drug Research Institute

Dr Avishek Saha

CSIR National Chemical Laboratory

Dr Avishek Saha

Central Scientific Instruments Organization

Dr Manoj Raje

N/A

Dr Pravinkumar Patil

Shivaji University

Prof Prabha Garg

National Institute of Pharmaceutical Education and Research (NIPER), Mohali

Dr Sidharth Chopra

Central Drug Research Institute

Dr Mushtaq Ahmad Wani

N/A

Scholarly Work

The relevance of host and Mycobacterial GAPDH during infection”

Funding Agency: Department of Science and Technology, Govt. of India

38.1 lakhs

2013 - 2016

Completed

Role of Mycobacterial GAPDH in Iron uptake

Funding Agency: Department of Biotechnology

52.49 lakhs

2010 - 2014

Completed

Role of GAPDH as a multifunctional protein in Dendritic cells

Funding Agency: Department of Science and Technology Women’s Scientist Scheme (A)

16.0 lakhs

2006 - 2009

Completed

Characterization of Mycobacterium tuberculosis H37Rv Glyceraldehyde-3-phosphate dehydrogenase (GAPDH, Rv1436) and its role in transferrin iron acquisition

University NIPER, SAS Nagar

Year 2016

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Scholarly Publications

Excess iron aggravates the severity of COVID-19 infection

Open Access

Article

Free Radical Biology and Medicine. Year: 2023. Volume: 208 , Pages: 186-193 .

Authors: Chaubey G.K.;Dilawari R.;Modanwal R.;Talukdar S.;Dhiman A.;Raje C.I.;Raje M.

10.1016/j.freeradbiomed.2023.08.011

Mycobacterium tuberculosis H37Rv enolase (Rv1023)- expression, characterization and effect of host dependent modifications on protein functionality

Open Access

Article

Biochimie. Year: 2023. Volume: 214 , Pages: 102-113 .

Authors: Kumar A.;Boradia V.M.;Mahajan A.;Kumaran S.;Raje M.;Raje C.I.

10.1016/j.biochi.2023.06.012

Solvent-Free Synthesis of S,N-Doped Carbon Dots for Extended Visible-Light-Induced Oxidase-Mimicking Activities and Antimicrobial Applications

Open Access

Article

CHEMPLUSCHEM. Year: 2023. Volume: 88 , Issue: 4 .

Authors: Kaushal N.;Jain A.;Kumar A.;Sarraf S.;Basu A.K.;Raje C.I.;Saha A.

10.1002/cplu.202300125

Characterization of the enzymatic and multifunctional properties of Acinetobacter baumannii erythrose-4-phosphate dehydrogenase (E4PDH)

Open Access

Article

Microbial Pathogenesis. Year: 2023. Volume: 175 .

Authors: Nimma R.;Kumar A.;Gani Z.;Gahlawat A.;Dilawari R.;Rohilla R.K.;Kumbhar H.;Garg P.;Chopra S.;Raje M.;Iyengar Raje C.

10.1016/j.micpath.2023.105992

Host glyceraldehyde-3-phosphate dehydrogenase-mediated iron acquisition is hijacked by intraphagosomal Mycobacterium tuberculosis

Open Access

Article

Cellular and Molecular Life Sciences. Year: 2022. Volume: 79 , Issue: 1 .

Authors: Patidar A.;Malhotra H.;Chaudhary S.;Kumar M.;Dilawari R.;Chaubey G.K.;Dhiman A.;Modanwal R.;Talukdar S.;Raje C.I.;Raje M.

10.1007/s00018-021-04110-3

Mycobacterium tuberculosis glyceraldehyde-3-phosphate dehydrogenase plays a dual role—As an adhesin and as a receptor for plasmin(ogen)

Open Access

Article

Year: 2021. Volume: 23 , Issue: 5 .

Authors: Gani Z.;Boradia V.M.;Kumar A.;Patidar A.;Talukdar S.;Choudhary E.;Singh R.;Agarwal N.;Raje M.;Iyengar Raje C.

10.1111/cmi.13311

Moonlighting glyceraldehyde-3-phosphate dehydrogenase (GAPDH) modulates protein aggregation

Open Access

Article

Year: 2021. Volume: 1867 , Issue: 10 .

Authors: Chaudhary S.;Dhiman A.;Patidar A.;Malhotra H.;Talukdar S.;Dilawari R.;Chaubey G.K.;Modanwal R.;Raje C.I.;Raje M.

10.1016/j.bbadis.2021.166202

Glyceraldehyde-3-Phosphate Dehydrogenase Facilitates Macroautophagic Degradation of Mutant Huntingtin Protein Aggregates

Open Access

Article

Year: 2021. Volume: 58 , Issue: 11 , Pages: 5790-5798 .

Authors: Chaudhary S.;Dhiman A.;Dilawari R.;Chaubey G.K.;Talukdar S.;Modanwal R.;Patidar A.;Malhotra H.;Raje C.I.;Raje M.

10.1007/s12035-021-02532-5

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