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Dr Patrick D' Silva

vidwan id: 54386
Male

Professor, Biochemistry
Indian Institute of Science Bangalore

Expertise

  • Cell Biology

Publications

Total Articles 54
Books 0
Proceedings 0

Publications

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Scopus

Citations 2946
h-index 27

CrossRef

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Citations 2937
h-index 26
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Professional Recognition

2004

Postdoctoral fellowship

American Heart Foundation, AHA
2006

Senior Postdoctoral fellowship

American Heart Foundation, AHA
2007

The Wellcome Trust Foundation-UK, Senior Research Fellowship in Biomedical Sciences.

Wellcome Trust Foundation-UK
2011

BM Birla Science Prize Award for Biological Sciences

Birla Science Foundation
2012

Young Researcher Award

Sir Dorabji Tata and allied Trust
2012

Swarnajayanthi Fellowship award in life sciences

Ministry of Science and Technology, DST, Government of India
2012

Nominated for GRC member

GRC
2014

National Bioscience award

Department of Biotechnology, India
2016

CDRI AWARDS -2016 for Excellence in Drug Research in Life Sciences

CSIR-Central Drug Research Institute, Lucknow.
2017

Sir. C.V. Raman Karnataka State Science award, Life Sciences

Karnataka, State
2017

Fellow of National Academy of Sciences

National Academy of Sciences (NASI), Allahabad
2024

Fellow of Indian Academy of Sciences

Indian Academy of Sciences, Bangalore

Community & Membership

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Bio

Chaperone Mediated Protein Folding in Cell, Mitochondrial Protein Transport, Heat Shock Protein-based Therapeutics, Iron-Sulphur (Fe-S) Proteins, Redox Biology, Mitochondrial dynamics, Nanobiology

Personal Details

  • Male
  • Professor , Indian Institute of Science Bangalore
  • Indian Institute of Science, Bangalore
Post Doc.
University of Wisconsin 2006
Ph.D.
Indian Institute of Technology Bombay 2000
MSc
Savitribai Phule Pune University 1995
BSc.
Other Institute 1993
Professor Jan 2019 – Present
Indian Institute of Science Bangalore | Biochemistry
Associate Professor Jan 2013 – Jan 2019
Indian Institute of Science Bangalore | Biochemistry
Assistant Professor Jan 2007 – Jan 2013
Unknown Organization

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Co-Authors (7)

Aloke

Dr Aloke Ghosh

Prabhat Kumar College

Amit

Dr Amit Ashok Vernekar

Central Leather Research Institute

Mugesh,

Prof Mugesh, G.

Indian Institute of Science Bangalore

Namrata

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Paramita

Dr Paramita Mukherjee

Variable Energy Cyclotron Centre (VECC),Kolkata

Praveen Kumar

Dr Praveen Kumar S K

Karnatak University

Scholarly Work

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Structure, function and dynamics of proteins by NMR spectroscopy: Application to human J-protein co -chaperone Dph4 and yeast Tim23-IMS

University Indian Institute of Science, Bangalore
Year 2012

Unraveling the intricate architecture of human mitochondrial presequence translocase – Insights on its evolution and role in tumourigenesis

University Indian Institute of Science, Bangalore
Year 2013

Role of Grp75 chaperone folding machinery in the maintenance of mitochondrial protein quality control

University Indian Institute of Science, Bangalore
Year 2013

Understanding the dynamic organization of the presequence-translocase in the translocation of preproteins across mitochondrial inner membrane

University Indian Institute of Science, Bangalore
Year 2014

Understanding in vivo significance of allosteric regularion in mtHsp70s: Revealing its implications in Parkinson’s disease progression

University Indian Institute of Science, Bangalore
Year 2015

Uncovering the role of mitochondrial iron-sulfur (Fe-S) cluster biogenesis in human health and disease

University Indian Institute of Science, Bangalore
Year 2015

Uncovering the role of mitochondrial co-chaperones and artificial antioxidants in cellular redox homeostasis

University Indian Institute of Science, Bangalore
Year 2016

Understanding the role of ThiJ/DJ-1/PfpI family member proteins in regulating redox homeostasis, mitochondrial health and lifespan in Saccharomyces cerevisiae

University Indian Institute of Science, Bangalore
Year 2017

Development of Nanomaterials as Antioxidant Enzyme Mimetics for Cellular Redox Homeostasis

University Indian Institute of Science, Bangalore
Year 2018

Investigating the role of Tim17 and Mgr2 in regulating the architecture of presequence translocase and mitochondrial health

University Indian Institute of Science, Bangalore
Year 2019

Understanding the structural organization of the carrier translocase machinery in regulating mitochondrial biogenesis and organelle quality control

University Indian Institute of Science, Bangalore
Year 2020

Understanding the architecture of mitochondrial presequence translocase machinery and its implications in ALS progression.

University Indian Institute of Science, Bangalore
Year 2022

Understanding the role of mtHsp70 in regulating mitochondrial homeostasis: revelaing its significance in Congenital Sideroblastic Anemia progression

University Indian Institute of Science, Bangalore
Year 2022

Understanding the role of DNAJC30 and ISCU in mitochondrial homeostasis

University Indian Institute of Science, Bangalore
Year 2024

Investigating DJ-1 homologs in maintaining genome integrity through glycation repair of macromolecules: Implications in regulating mitochondrial health

University Indian Institute of Science, Bangalore
Year 2024

Deciphering the Role of DJ-1 Homologs in Alleviating Carbonyl and Oxidative Stress in Arabidopsis thaliana

University Indian Institute of Science, Bangalore
Year 2024
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Scholarly Publications

Ubp2 modulates DJ-1-mediated redox-dependent mitochondrial dynamics in Saccharomyces cerevisiae

Open Access
Article

Seahorse assay for the analysis of mitochondrial respiration using Saccharomyces cerevisiae as a model system

Open Access
Article

A histidine-functionalized ROS scavenging hybrid nanozyme for therapeutic application in Parkinson's disease pathogenesis

Open Access
Article

Saccharomyces cerevisiae DJ-1 paralogs maintain genome integrity through glycation repair of nucleic acids and proteins

Open Access
Article
Authors: Susarla G.;Kataria P.;Kundu A.;D'Silva P.

Functional crosstalk between the TIM22 complex and YME1 machinery maintains mitochondrial proteostasis and integrity

Open Access
Article

A journey through the gateway of polytopic inner membrane proteins: the carrier translocase machinery

Open Access
Review

Loss of Function of mtHsp70 Chaperone Variants Leads to Mitochondrial Dysfunction in Congenital Sideroblastic Anemia

Open Access
Article

Double DJ-1 domain containing Arabidopsis DJ-1D is a robust macromolecule deglycase

Open Access
Article
Authors: Prasad M.;Kataria P.;Ningaraju S.;Buddidathi R.;Bankapalli K.;Swetha C.;Susarla G.;Venkatesan R.;D'Silva P.;Shivaprasad P.V.