Dr Patrick D' Silva
vidwan id: 54386
Professor, Biochemistry
Indian Institute of Science Bangalore
Expertise
- Cell Biology
Publications
Publications
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Scopus
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27
CrossRef
Citations
2937
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26
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Professional Recognition
Postdoctoral fellowship
American Heart Foundation, AHASenior Postdoctoral fellowship
American Heart Foundation, AHAThe Wellcome Trust Foundation-UK, Senior Research Fellowship in Biomedical Sciences.
Wellcome Trust Foundation-UKBM Birla Science Prize Award for Biological Sciences
Birla Science FoundationYoung Researcher Award
Sir Dorabji Tata and allied TrustSwarnajayanthi Fellowship award in life sciences
Ministry of Science and Technology, DST, Government of IndiaNominated for GRC member
GRCNational Bioscience award
Department of Biotechnology, IndiaCDRI AWARDS -2016 for Excellence in Drug Research in Life Sciences
CSIR-Central Drug Research Institute, Lucknow.Sir. C.V. Raman Karnataka State Science award, Life Sciences
Karnataka, StateFellow of National Academy of Sciences
National Academy of Sciences (NASI), AllahabadFellow of Indian Academy of Sciences
Indian Academy of Sciences, BangaloreCommunity & Membership
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Bio
Chaperone Mediated Protein Folding in Cell, Mitochondrial Protein Transport, Heat Shock Protein-based Therapeutics, Iron-Sulphur (Fe-S) Proteins, Redox Biology, Mitochondrial dynamics, Nanobiology
Personal Details
- Male
- Professor , Indian Institute of Science Bangalore
- Indian Institute of Science, Bangalore
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Dr Jyothi Alias Jyotsna Baragi
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Co-Authors (7)
Prabhat Kumar College
Central Leather Research Institute
Indian Institute of Science Bangalore
Central Drug Research Institute
Variable Energy Cyclotron Centre (VECC),Kolkata
Karnatak University
Scholarly Work
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Structure, function and dynamics of proteins by NMR spectroscopy: Application to human J-protein co -chaperone Dph4 and yeast Tim23-IMS
Unraveling the intricate architecture of human mitochondrial presequence translocase – Insights on its evolution and role in tumourigenesis
Role of Grp75 chaperone folding machinery in the maintenance of mitochondrial protein quality control
Understanding the dynamic organization of the presequence-translocase in the translocation of preproteins across mitochondrial inner membrane
Understanding in vivo significance of allosteric regularion in mtHsp70s: Revealing its implications in Parkinson’s disease progression
Uncovering the role of mitochondrial iron-sulfur (Fe-S) cluster biogenesis in human health and disease
Uncovering the role of mitochondrial co-chaperones and artificial antioxidants in cellular redox homeostasis
Understanding the role of ThiJ/DJ-1/PfpI family member proteins in regulating redox homeostasis, mitochondrial health and lifespan in Saccharomyces cerevisiae
Development of Nanomaterials as Antioxidant Enzyme Mimetics for Cellular Redox Homeostasis
Investigating the role of Tim17 and Mgr2 in regulating the architecture of presequence translocase and mitochondrial health
Understanding the structural organization of the carrier translocase machinery in regulating mitochondrial biogenesis and organelle quality control
Understanding the architecture of mitochondrial presequence translocase machinery and its implications in ALS progression.
Understanding the role of mtHsp70 in regulating mitochondrial homeostasis: revelaing its significance in Congenital Sideroblastic Anemia progression
Understanding the role of DNAJC30 and ISCU in mitochondrial homeostasis
Investigating DJ-1 homologs in maintaining genome integrity through glycation repair of macromolecules: Implications in regulating mitochondrial health
Deciphering the Role of DJ-1 Homologs in Alleviating Carbonyl and Oxidative Stress in Arabidopsis thaliana
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Scholarly Publications
Molecular insights revealing interaction of Tim23 and channel subunits of presequence translocase
Open Access
10.1128/MCB.00876-13
24
22
Enhanced J-protein interaction and compromised protein stability of mtHsp70 variants lead to mitochondrial dysfunction in parkinson's disease
Open Access
10.1093/hmg/dds162
35
34
Structure and mechanistic insights into novel iron-mediated moonlighting functions of human J-protein cochaperone, Dph4
Open Access
10.1074/jbc.M112.339655
30
28
Primary sequence that determines the functional overlap between mitochondrial heat shock protein 70 Ssc1 and Ssc3 of Saccharomyces cerevisiae
Open Access
10.1074/jbc.M110.197434
16
15
Amino acid selective unlabeling for sequence specific resonance assignments in proteins
Open AccessHigh-resolution methyl edited GFT NMR experiments for protein resonance assignments and structure determination
Open AccessRole of Magmas in protein transport and human mitochondria biogenesis
Open Access
10.1093/hmg/ddq002
59
57