Ministry of Education
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Dr Sathees C Raghavan

vidwan id: 54383
Male

Professor, Biochemistry
Indian Institute of Science Bangalore

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Expertise

  • Genetics and Heredity

Publications

Total Articles 168
Books 0
Proceedings 0

Publications

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Scopus

Citations 6497
h-index 45

CrossRef

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Citations 6011
h-index 44
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Professional Recognition

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Community & Membership

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Bio

Cancer Genetics, Genomic Instability, DNA Repair and Recombination.

Personal Details

  • Male
  • Professor , Indian Institute of Science Bangalore
  • C V Raman Avenue,
Post Doctoral
Other Institute 2006
Ph.D.
Banaras Hindu University 1999
Professor Jan 2019 – Present
Indian Institute of Science Bangalore | Biochemistry

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Co-Authors (43)

Abhijit

Dr Abhijit De

Advanced Centre for Treatment, Research and Education in Cancer

Anjali Anoop

Prof Anjali Anoop Karande

Indian Institute of Science Bangalore

Anupam

Prof Anupam Chatterjee

North Eastern Hill University

Atanu

Dr Atanu Banerjee

Assam University

K. N.

Dr K. N. Balaji

Indian Institute of Science Bangalore

Ananda Kumar

Dr Ananda Kumar C

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Dr SUJEET KUMAR

NITTE COLLEGE OF PHARMACEUTICAL SCIENCES

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Dr Girish YR

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Dr Jinu George

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Prof K. Kemparaju

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Kempegowda

Dr Kempegowda Mantelingu

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Prof K. Muniyappa

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Girish

Dr Girish K S

Tumkur University

Madhusudan

Dr Madhusudan Purohit

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Mridula

Dr Mridula Nambiar

Indian Institute of Science Education and Research(IISER), Pune

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Dr Mrinal Srivastava

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Gopal M

Prof Gopal M Advirao

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Dr Ganesh Nagaraju

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Dr Prabhu V

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Dr Prasanna D. Shivaramu

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Pritha

Dr Pritha Ray

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Kanchugarakoppal S

Prof Kanchugarakoppal S Rangappa

University of Mysore

Ranjit Kumar

Prof Ranjit Kumar Giri

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Sanjay Kumar

Dr Sanjay Kumar Raul

RAMA DEVI WOMEN'S UNIVERSITY, BHUBANESWAR

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Dr Nagalingam Ravi Sundaresan

Indian Institute of Science Bangalore

Basappa

Dr Basappa

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Santanu

Prof Santanu Bhattacharya

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Kothanahally S

Dr Kothanahally S SharathKumar

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Dr Shobith Rangappa

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Dr Srinivasan Raghavan

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Dr Swarup H A

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Dr Chinnasamy Thirunavukkarasu

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Dr V K Aswal

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Scholarly Work

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DNA Double-Strand Break Repair : Molecular Characterization of Classical and Alternative Nonhomologous End Joining in Mitochondrial and Cell-free Extracts

University Indian Institute of Science banglore
Year 2013

Evaluation of Alternate DNA Structures at c-MYC Fragile Region Associated with t(8;14) Translocation And Role of GNG Motifs During G-quadruplex Formation

University Indian Institute of Science banglore
Year 2016

Identification and Biochemical Characterization of Novel Inhibitors of Nonhomologous End Joining: Implications in DNA Double-Strand Break Repair and Cancer Therapy

University Indian Institute of Science banglore
Year 2020

Investigating DNA structural basis for fragility during chromosomal translocations associated with human B-cell lymphomas

University Indian Institute of Science banglore
Year 2019

Investigation of RAG1 in lymphoid and brain cells: Understanding mechanism and regulation

University Indian Institute of Science banglore
Year 2020

The Mechanism Of Fragility Of The BCL2 And HOX11 Breakpoint Regions During t(14;18) And t(10;14) Chromosomal Translocations In Lymphoid Cancers

University Indian Institute of Science banglore
Year 2011

Mechanism Of RAG Action As A Structure-Specific Nuclease : Implications In Genomic Instability In Lymphoid Cells

University Indian Institute of Science banglore
Year 2011

Mechanism of RAG Regulation During Its Physiological and Pathological Functions in Lymphoid Cells

University Indian Institute of Science banglore
Year 2015

Molecular Insights into Lymphoid Malignancy : Role of Transcription Factor BCL11B in T-cell Leukemia Genesis and Biochemical Characterization of DNA Binding Domain of RAG1

University Indian Institute of Science banglore
Year 2017

Physiological And Exogenous Means of Regulating DNA Damage Response : Insights into Mechanisms of DNA Repair And Genomic Instability

University Indian Institute of Science banglore
Year 2016

Understanding the Mechanism of Double-strand Break Repair and Genome Fragility in Mammalian Mitochondria

University Indian Institute of Science banglore
Year 2019

Understanding the Sequence Dependence of NHEJ Mediated Double-strand Break Repair, and Identification of Novel DNA Ligase Inhibitors and their Potential Use as Cancer Therapeutics

University Indian Institute of Science banglore
Year 2017

Mercaptopyrimidine compounds that inhibit nonhomologous end joining and methods thereof

INDIAN INSTITUTE OF SCIENCE UNIVERSITY OF MYSORE
- Patent No. : WO2023/126980 Filed : 31-12-2021
Published : 06-07-2023 Published

Mercaptopyrimidine compounds that inhibit nonhomologous end joining and methods thereof

INDIAN INSTITUTE OF SCIENCE
- Patent No. : IN504195 Filed : 31-12-2021
Published : 17-02-2023 Published

NOVEL INHIBITORS OF ANTIAPOPTOTIC BCL-2 PROTEIN

Indian Institute Of Science
- Patent No. : 386398 Filed : 27-04-2017
Published : 11-01-2022 Granted

Compounds as inhibitor of DNA double-strand break repair, methods and applications thereof

INDIAN INSTITUTE OF SCIENCE
Karnataka
IN | INDIAN INSTITUTE OF SCIENCE
Bangalore
Karnataka
IN | INDIAN INST SCIENT
- Patent No. : US9969696B2 Filed : 05-01-2015
Published : 15-05-2018 Published

COMPOUNDS AS INHIBITOR OF DNA DOUBLE-STRAND BREAK REPAIR, METHODS AND APPLICATIONS THEREOF

INDIAN INSTITUTE OF SCIENCE
Bangalore
Karnataka
IN | INDIAN INST SCIENT
- Patent No. : US20150158822A1 Filed : 05-01-2015
Published : 11-06-2015 Published

Compounds as inhibitor of DNA double-strand break repair, methods and applications thereof

INDIAN INST SCIENT
IN | INDIAN INST SCIENT
- Patent No. : GB2523674B Filed : 07-03-2013
Published : 11-03-2020 Published

COMPOSÉS INHIBITEURS DE LA RÉPARATION DE LA CASSURE DOUBLE BRIN DE L'ADN, PROCÉDÉS ET APPLICATIONS CORRESPONDANTS | COMPOUNDS AS INHIBITOR OF DNA DOUBLE-STRAND BREAK REPAIR, METHODS AND APPLICATIONS THEREOF

INDIAN INSTITUTE OF SCIENCE
IN
- Patent No. : WO2014006518A1 Filed : 07-03-2013
Published : 09-01-2014 Published

Compounds as inhibitor of DNA double-strand break repair, methods and applications thereof

Indian Institute of Science
IN | INDIAN INST SCIENT
- Patent No. : GB2523674A Filed : 07-03-2013
Published : 02-09-2015 Published

COMPOUNDS AS INHIBITOR OF DNA DOUBLE-STRAND BREAK REPAIR METHODS AND APPLICATIONS THEREOF

INDIAN INSTITUTE OF SCIENCE | KLE UNIVERSITYS COLLEGE OF PHARMACY
- Patent No. : IN316878B Filed : 04-07-2012
Published : 02-08-2019 Published

COMPOUNDS AS INHIBITOR OF DNA DOUBLE-STRAND BREAK REPAIR METHODS AND APPLICATIONS THEREOF

INDIAN INSTITUTE OF SCIENCE | KLE UNIVERSITYS COLLEGE OF PHARMACY
- Patent No. : IN201202713I4 Filed : 04-07-2012
Published : 15-01-2016 Published

Scholarly Publications

Regulation of pathway choice in DNA repair after double-strand breaks

Open Access
Review
Current Opinion in Pharmacology. Year: 2025. Volume: 80 .
Authors: Kumari N.;Kaur E.;Raghavan S.C.;Sengupta S.
DOI 10.1016/j.coph.2024.102496
6

Biological evaluation of novel 5-((1H-indol-3-yl) methyl)-2-(4-chlorobenzyl)-6-phenyl-imidazo[2,1-b][13,4]thiadiazole derivatives as novel BCL-2 specific inhibitors

Open Access
Article
European Journal of Medicinal Chemistry Reports. Year: 2025. Volume: 13 .
Authors: Sharma S.;Shamanth S.;Siddiqua H.;Goyary L.;Sagar K.S.;Kumari S.;Sathees D.;Radha G.;Choudhary B.;Raghavan S.C.;Mantelingu K.
DOI 10.1016/j.ejmcr.2025.100247

Formation of multiple G-quadruplexes contributes toward BCR fragility associated with chronic myelogenous leukemia

Open Access
Article
Nucleic Acids Research. Year: 2025. Volume: 53 , Issue: 6 .
Authors: Sharma S.;Thomas E.;Dahal S.;Das S.;Kothari S.;Roy U.;Kumari N.;Gopalakrishnan V.;Raghavan S.C.
DOI 10.1093/nar/gkaf167

A novel approach toward the multigram synthesis of a novel Bcl2-specific inhibitor, and evaluation of its biological activity

Open Access
Article
European Journal of Medicinal Chemistry Reports. Year: 2024. Volume: 11 .
Authors: Raveendran M.;Sharma S.;Palimkar S.S.;Lakshmana Kumar M.;Sahana H.;Swarup H.A.;Raghavan S.C.
DOI 10.1016/j.ejmcr.2024.100157

Delineating the mechanism of fragility at BCL6 breakpoint region associated with translocations in diffuse large B cell lymphoma

Open Access
Article
Cellular and Molecular Life Sciences. Year: 2024. Volume: 81 , Issue: 1 .
Authors: Gopalakrishnan V.;Roy U.;Srivastava S.;Kariya K.M.;Sharma S.;Javedakar S.M.;Choudhary B.;Raghavan S.C.
DOI 10.1007/s00018-023-05042-w
5 4

Disarib, a Specific BCL2 Inhibitor, Induces Apoptosis in Triple-Negative Breast Cancer Cells and Impedes Tumour Progression in Xenografts by Altering Mitochondria-Associated Processes

Open Access
Article
International Journal of Molecular Sciences. Year: 2024. Volume: 25 , Issue: 12 .
Authors: Manjunath M.;Ravindran F.;Sharma S.;Siddiqua H.;Raghavan S.C.;Choudhary B.
DOI 10.3390/ijms25126485
4 4

Understanding the Role of miR-29a in the Regulation of RAG1, a Gene Associated with the Development of the Immune System

Open Access
Article
Year: 2024. Volume: 213 , Issue: 8 , Pages: 1125-1138 .
Authors: Roy U.;Desai S.S.;Kumari S.;Bushra T.;Choudhary B.;Raghavan S.C.
DOI 10.4049/jimmunol.2300344
1 2

Mutations at BCL11B Exon 4 Associated with T Cell Acute Lymphoblastic Leukemia Are Facilitated by AID and Formation of Non-B DNA Conformations

Open Access
Article
Molecular and Cellular Biology. Year: 2024. Volume: 44 , Issue: 12 , Pages: 590-606 .
Authors: Roy U.;Sharma A.;Sharma S.;Dahal S.;Kumari N.;Desai S.S.;Kumari S.;Dixit J.;Sharma M A.;Nujoom N.;Choudhary B.;Raghavan S.C.
DOI 10.1080/10985549.2024.2419661
1