Ministry of Education
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Dr Sathees C Raghavan

vidwan id: 54383
Male

Professor, Biochemistry
Indian Institute of Science Bangalore

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Expertise

  • Genetics and Heredity

Publications

Total Articles 168
Books 0
Proceedings 0

Publications

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Scopus

Citations 6497
h-index 45

CrossRef

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Citations 6011
h-index 44
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Professional Recognition

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Bio

Cancer Genetics, Genomic Instability, DNA Repair and Recombination.

Personal Details

  • Male
  • Professor , Indian Institute of Science Bangalore
  • C V Raman Avenue,
Post Doctoral
Other Institute 2006
Ph.D.
Banaras Hindu University 1999
Professor Jan 2019 – Present
Indian Institute of Science Bangalore | Biochemistry

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Organisations (660+)

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Dr Balachandra Suri

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Co-Authors (43)

Abhijit

Dr Abhijit De

Advanced Centre for Treatment, Research and Education in Cancer

Anjali Anoop

Prof Anjali Anoop Karande

Indian Institute of Science Bangalore

Anupam

Prof Anupam Chatterjee

North Eastern Hill University

Atanu

Dr Atanu Banerjee

Assam University

K. N.

Dr K. N. Balaji

Indian Institute of Science Bangalore

Ananda Kumar

Dr Ananda Kumar C

Visvesvaraya Technological University, Belagavi

SUJEET

Dr SUJEET KUMAR

NITTE COLLEGE OF PHARMACEUTICAL SCIENCES

Girish

Dr Girish YR

Adichunchanagiri University

Jinu

Dr Jinu George

S H College, Thevara

K.

Prof K. Kemparaju

University of Mysore

Kempegowda

Dr Kempegowda Mantelingu

University of Mysore

K.

Prof K. Muniyappa

Indian Institute of Science Bangalore

Girish

Dr Girish K S

Tumkur University

Madhusudan

Dr Madhusudan Purohit

JSS Academy of Higher Education & Research

Mridula

Dr Mridula Nambiar

Indian Institute of Science Education and Research(IISER), Pune

Mrinal

Dr Mrinal Srivastava

N/A

Srivastava

Dr Srivastava Mrinal

Tata Institute of Fundamental Research Hyderabad

Gopal M

Prof Gopal M Advirao

Davangere University

Ramanathan

Dr Ramanathan Natesh

Indian Institute of Science Education and Research(IISER), Thiruvanthpuram

Ganesh

Dr Ganesh Nagaraju

Indian Institute of Science Bangalore

Nishana

Dr Nishana Mayilaadumveettil

Indian Institute of Science Education and Research(IISER), Thiruvanthpuram

Prabhu

Dr Prabhu V

N/A

Prasanna

Dr Prasanna D. Shivaramu

Visvesvaraya Technological University, Belagavi

Pritha

Dr Pritha Ray

Advanced Centre for Treatment, Research and Education in Cancer

Kanchugarakoppal S

Prof Kanchugarakoppal S Rangappa

University of Mysore

Ranjit Kumar

Prof Ranjit Kumar Giri

National Brain Research Centre, Gurgaon

Sanjay Kumar

Dr Sanjay Kumar Raul

RAMA DEVI WOMEN'S UNIVERSITY, BHUBANESWAR

Nagalingam Ravi

Dr Nagalingam Ravi Sundaresan

Indian Institute of Science Bangalore

Basappa

Dr Basappa

University of Mysore

Santanu

Prof Santanu Bhattacharya

Indian Institute of Science Bangalore

Kothanahally S

Dr Kothanahally S SharathKumar

University of Mysore

Shobith

Dr Shobith Rangappa

Adichunchanagiri University

Sandip Kumar

Dr Sandip Kumar Nayak

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Srinivasan

Dr Srinivasan Raghavan

Indian Institute of Science Bangalore

subhas s

Dr subhas s karki

KLE College of Pharmacy, Bangalore

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A. Surolia

Indian Institute of Science Bangalore

Swarup

Dr Swarup H A

B N M Institute of Technology, Bangalore

Nagini

Dr Nagini Siddavaram

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Dr Chinnasamy Thirunavukkarasu

Pondicherry University

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Prof Umesh Varshney

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Prof Bibha Choudhary

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Vivek

Prof Vivek Tripathi

Nitte University Centre for Science Education and Research

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Dr V K Aswal

Bhabha Atomic Research Centre (BARC), Mumbai

Scholarly Work

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DNA Double-Strand Break Repair : Molecular Characterization of Classical and Alternative Nonhomologous End Joining in Mitochondrial and Cell-free Extracts

University Indian Institute of Science banglore
Year 2013

Evaluation of Alternate DNA Structures at c-MYC Fragile Region Associated with t(8;14) Translocation And Role of GNG Motifs During G-quadruplex Formation

University Indian Institute of Science banglore
Year 2016

Identification and Biochemical Characterization of Novel Inhibitors of Nonhomologous End Joining: Implications in DNA Double-Strand Break Repair and Cancer Therapy

University Indian Institute of Science banglore
Year 2020

Investigating DNA structural basis for fragility during chromosomal translocations associated with human B-cell lymphomas

University Indian Institute of Science banglore
Year 2019

Investigation of RAG1 in lymphoid and brain cells: Understanding mechanism and regulation

University Indian Institute of Science banglore
Year 2020

The Mechanism Of Fragility Of The BCL2 And HOX11 Breakpoint Regions During t(14;18) And t(10;14) Chromosomal Translocations In Lymphoid Cancers

University Indian Institute of Science banglore
Year 2011

Mechanism Of RAG Action As A Structure-Specific Nuclease : Implications In Genomic Instability In Lymphoid Cells

University Indian Institute of Science banglore
Year 2011

Mechanism of RAG Regulation During Its Physiological and Pathological Functions in Lymphoid Cells

University Indian Institute of Science banglore
Year 2015

Molecular Insights into Lymphoid Malignancy : Role of Transcription Factor BCL11B in T-cell Leukemia Genesis and Biochemical Characterization of DNA Binding Domain of RAG1

University Indian Institute of Science banglore
Year 2017

Physiological And Exogenous Means of Regulating DNA Damage Response : Insights into Mechanisms of DNA Repair And Genomic Instability

University Indian Institute of Science banglore
Year 2016

Understanding the Mechanism of Double-strand Break Repair and Genome Fragility in Mammalian Mitochondria

University Indian Institute of Science banglore
Year 2019

Understanding the Sequence Dependence of NHEJ Mediated Double-strand Break Repair, and Identification of Novel DNA Ligase Inhibitors and their Potential Use as Cancer Therapeutics

University Indian Institute of Science banglore
Year 2017

Mercaptopyrimidine compounds that inhibit nonhomologous end joining and methods thereof

INDIAN INSTITUTE OF SCIENCE UNIVERSITY OF MYSORE
- Patent No. : WO2023/126980 Filed : 31-12-2021
Published : 06-07-2023 Published

Mercaptopyrimidine compounds that inhibit nonhomologous end joining and methods thereof

INDIAN INSTITUTE OF SCIENCE
- Patent No. : IN504195 Filed : 31-12-2021
Published : 17-02-2023 Published

NOVEL INHIBITORS OF ANTIAPOPTOTIC BCL-2 PROTEIN

Indian Institute Of Science
- Patent No. : 386398 Filed : 27-04-2017
Published : 11-01-2022 Granted

Compounds as inhibitor of DNA double-strand break repair, methods and applications thereof

INDIAN INSTITUTE OF SCIENCE
Karnataka
IN | INDIAN INSTITUTE OF SCIENCE
Bangalore
Karnataka
IN | INDIAN INST SCIENT
- Patent No. : US9969696B2 Filed : 05-01-2015
Published : 15-05-2018 Published

COMPOUNDS AS INHIBITOR OF DNA DOUBLE-STRAND BREAK REPAIR, METHODS AND APPLICATIONS THEREOF

INDIAN INSTITUTE OF SCIENCE
Bangalore
Karnataka
IN | INDIAN INST SCIENT
- Patent No. : US20150158822A1 Filed : 05-01-2015
Published : 11-06-2015 Published

Compounds as inhibitor of DNA double-strand break repair, methods and applications thereof

INDIAN INST SCIENT
IN | INDIAN INST SCIENT
- Patent No. : GB2523674B Filed : 07-03-2013
Published : 11-03-2020 Published

COMPOSÉS INHIBITEURS DE LA RÉPARATION DE LA CASSURE DOUBLE BRIN DE L'ADN, PROCÉDÉS ET APPLICATIONS CORRESPONDANTS | COMPOUNDS AS INHIBITOR OF DNA DOUBLE-STRAND BREAK REPAIR, METHODS AND APPLICATIONS THEREOF

INDIAN INSTITUTE OF SCIENCE
IN
- Patent No. : WO2014006518A1 Filed : 07-03-2013
Published : 09-01-2014 Published

Compounds as inhibitor of DNA double-strand break repair, methods and applications thereof

Indian Institute of Science
IN | INDIAN INST SCIENT
- Patent No. : GB2523674A Filed : 07-03-2013
Published : 02-09-2015 Published

COMPOUNDS AS INHIBITOR OF DNA DOUBLE-STRAND BREAK REPAIR METHODS AND APPLICATIONS THEREOF

INDIAN INSTITUTE OF SCIENCE | KLE UNIVERSITYS COLLEGE OF PHARMACY
- Patent No. : IN316878B Filed : 04-07-2012
Published : 02-08-2019 Published

COMPOUNDS AS INHIBITOR OF DNA DOUBLE-STRAND BREAK REPAIR METHODS AND APPLICATIONS THEREOF

INDIAN INSTITUTE OF SCIENCE | KLE UNIVERSITYS COLLEGE OF PHARMACY
- Patent No. : IN201202713I4 Filed : 04-07-2012
Published : 15-01-2016 Published

Scholarly Publications

Evaluation of potential role of R-loop and G-quadruplex DNA in the fragility of c-MYC during chromosomal translocation associated with Burkitt's lymphoma

Open Access
Article
JOURNAL OF BIOLOGICAL CHEMISTRY. Year: 2023. Volume: 299 , Issue: 12 .
Authors: Kumari N.;Das K.;Sharma S.;Dahal S.;Desai S.S.;Roy U.;Sharma A.;Manjunath M.;Gopalakrishnan V.;Retheesh S.T.;Javadekar S.M.;Choudhary B.;Raghavan S.C.
DOI 10.1016/j.jbc.2023.105431
3 9

Identification and characterization of mercaptopyrimidine-based small molecules as inhibitors of nonhomologous DNA end joining

Open Access
Article
Year: 2023. Volume: 290 , Issue: 3 , Pages: 796-820 .
Authors: Ray U.;Gopinatha V.K.;Sharma S.;Goyary L.;Choudhary B.;Mantelingu K.;Rangappa K.S.;Raghavan S.C.
DOI 10.1111/febs.16615
9 8

Deficiency of ligase IV leads to reduced NHEJ, accumulation of DNA damage, and can sensitize cells to cancer therapeutics

Open Access
Article
Year: 2023. Volume: 115 , Issue: 6 .
Authors: Kumari N.;Antil H.;Kumari S.;Raghavan S.C.
DOI 10.1016/j.ygeno.2023.110731
7 7

Block Copolymer Encapsulation of Disarib, an Inhibitor of BCL2 for Improved Chemotherapeutic Potential

Open Access
Article
ACS Omega. Year: 2023. Volume: 8 , Issue: 43 , Pages: 40729-40740 .
Authors: Joy R.;Siddiqua H.;Sharma S.;Raveendran M.;John F.;Hassan P.A.;Gawali S.L.;Raghavan S.C.;George J.
DOI 10.1021/acsomega.3c05802
3 3

MicroRNA, miR-501 regulate the V(D)J recombination in B cells

Open Access
Article
Biochemical Journal. Year: 2023. Volume: 480 , Issue: 24 , Pages: 2061-2077 .
Authors: Kumari R.;Roy U.;Desai S.;Mondal A.S.;Nair R.R.;Nilavar N.;Choudhary B.;Raghavan S.C.
DOI 10.1042/BCJ20230250
2 4

Design and Synthesis of Ketenimine Sulfonamide Conjugates through Multicomponent Reactions; A Combined Cytotoxic Analysis and Computational Exploration

Open Access
Article
ACS Omega. Year: 2023. Volume: 8 , Issue: 41 , Pages: 38619-38631 .
Authors: Prabhu D.J.;Ray U.;Rajeev A.;Joy R.;George A.T.;George J.;Raghavan S.C.;John F.
DOI 10.1021/acsomega.3c05816

MiRAGDB: A Knowledgebase of RAG Regulators

Open Access
Article
Frontiers in Immunology. Year: 2022. Volume: 13 .
Authors: Desai S.S.;Whadgar S.;Raghavan S.C.;Choudhary B.
DOI 10.3389/fimmu.2022.863110
4 4

A novel KU70-mutant human leukemic cell line generated using CRISPR-Cas9 shows increased sensitivity to DSB inducing agents and reduced NHEJ activity

Open Access
Article
Year: 2022. Volume: 1866 , Issue: 12 .
Authors: Ghosh D.;Nilavar N.M.;Raghavan S.C.
DOI 10.1016/j.bbagen.2022.130246
1 2