Ministry of Education
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Dr Sam Mathew

vidwan id: 430688
Male

Associate Professor,
Regional Centre for Biotechnology

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Expertise

  • Developmental Biology

Publications

Total Articles 7
Books 0
Proceedings 0

Publications

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Scopus

Citations 8
h-index 1

CrossRef

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Citations 7
h-index 1
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Professional Recognition

2013

Wellcome DBT Intermediate Fellowship

Wellcome Trust DBT
2023

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EMBO Molecular Medicine
2022

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Journal of Cell Science
2019

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Developmental Biology

Community & Membership

2023

RCB Institutional Biosafety Committee

Member
2023

RCB Institutional Animal Ethics Committee

Member Secretary

Indian Society for Developmental Biology

2018
Member

Bio

We are studying the mammalian skeletal muscle and its role in diseases. We use genetics, cell biology, biochemistry and molecular biology tools in our studies.

Personal Details

  • Male
  • Associate Professor , Regional Centre for Biotechnology
  • 3rd Milestone
PhD
University of Cologne, Germany 2006
MSc
Other Institute 1998
Associate Professor Sep 2012 – Present
Regional Centre for Biotechnology

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Organisations (4+)

Arup

Dr Arup Banerjee

Associate Professor

Ankita

Dr Ankita Alexander

Research Fellow

Vengadesan

Dr Vengadesan Krishnan

Professor

Sam

Dr Sam Mathew

Associate Professor

Ramu

Dr Ramu Vemanna

Assistant Professor

Co-Authors (0)

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Scholarly Work

The Role of Transducin-like Enhancer of Split 3 (TLE3) in Regulating Myogenesis File No : EMR/2016/005218/AS (Ver-1) Submitted By

Funding Agency: SERB

Principal Investigator

4,517,471

2017 - 2021

Completed
The role of MET-CBL signaling in rhabdomyosarcoma

Funding Agency: DBT

Principal Investigator

2,454,000

2015 - 2019

Completed
The role of developmental Myosin Heavy Chains in skeletal muscle development, regeneration, homeostasis and disease

Funding Agency: Wellcome DBT India Alliance

Principal Investigator

33,148,467

2014 - 2020

Completed

INVESTIGATION OF REGULATORY MOLECULES INVOLVED IN MAMMALIAN SKELETAL MUSCLE DIFFERENTIATION

University Manipal University
Year 2020

Drosophila as a model to study the role of human embryonic Myosin Heavy Chain associated congenital myopathies

University Regional Centre for Biotechnology
Year 2022

REGULATION OF SKELETAL MUSCLE DIFFERENTIATION DURING DROSOPHILA AND MAMMALIAN MYOGENESIS

University Manipal University
Year 2022

Characterization of the role of Myosin Heavy Chains (MyHCs) in Mammalian Skeletal Muscle Development and Disease

University Kalinga Institute of Industrial Technology
Year 2023
No Data Found

There is currently nothing to display here.

Scholarly Publications

Musculoskeletal defects associated with myosin heavy chain-embryonic loss of function are mediated by the YAP signaling pathway.

Open Access
article
EMBO Molecular Medicine. Year: 2023. Volume: 15(9):e17187 .
Authors: Bharadwaj, A*., J. Sharma*, Singh, J., Kumari, M., Dargar, T., Kalita, B., and S.J. Mathew
DOI 10.15252/emmm.202217187

Zeb1 and Tle3 are trans-factors that differentially regulate the expression of myosin heavy chain-embryonic and skeletal muscle differentiation.

Open Access
article
Year: 2023. Volume: 37(8):e23074 .
Authors: Kumar, P., Zehra, A., Saini, M., and Mathew, S. J.
DOI 10.1096/fj.202201698RR.

TLE4 regulates muscle stem cell quiescence and skeletal muscle differentiation.

Open Access
article
Journal of Cell Science. Year: 2022. Volume: 135(4) .
Authors: Agarwal, M*., A. Bharadwaj*, and S.J. Mathew.
DOI 10.1242/jcs.256008

Ribosome-associated quality control mediates degradation of the premature translation termination product Orf1p of ODC antizyme mRNA.

Open Access
article
FEBS LETTERS. Year: 2021. Volume: 595 , Pages: 2015-2033 .
Authors: Pradhan AK, G. Kandasamy, U. Chatterjee, A. Bharadwaj, S.J. Mathew, R.J. Dohmen, and Palanimurugan R.
DOI 10.1002/1873-3468.14147

Myosin heavy chain-embryonic regulates skeletal muscle differentiation during mammalian development

Open Access
Article
Year: 2020. Volume: 147 , Issue: 7 .
Authors: Megha Agarwal ., Akashi Sharma ., Pankaj Kumar ., Amit Kumar ., Anushree Bharadwaj ., Masum Saini ., Gabrielle Kardon ., Sam J. Mathew .,
DOI 10.1242/dev.184507
7 8

Myosin heavy chain mutations that cause Freeman-Sheldon syndrome lead to muscle structural and functional defects in Drosophila.

Open Access
article
Year: 2019. Volume: 449(2) , Pages: 90-98 .
Authors: Das, S., P. Kumar, A. Verma, T. K. Maiti, and S.J. Mathew.
DOI 10.1016/j.ydbio.2019.02.017

SPRY2 is a novel MET regulator that regulates metastatic potential and differentiation in rhabdomyosarcoma.

Open Access
article
Year: 2018. Volume: 9(2): 237 .
Authors: Saini, M., A. Verma, and S.J. Mathew.
DOI 10.1038/s41419-018-0261-2