Ministry of Education
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Prof Rajesh Kumar Gandhirajan

vidwan id: 275632
Male

Professor, Department of Human Genetics
Sri Ramachandra Institute of Higher Education and Research

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Expertise

  • Biology

Publications

Total Articles 71
Books 0
Proceedings 0

Publications

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Scopus

Citations 2013
h-index 24

CrossRef

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Citations 1779
h-index 23
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SOCIETY FOR REDOX BIOLOGY AND MEDICINE

2021
Life

Bio

Biochemist, Hands on experience in drug screening, high content imaging, phenologic analysis, high throughput gene expression analysis and target validation in vitro and in vivo

Personal Details

  • Male
  • Professor , Sri Ramachandra Institute of Higher Education and Research
  • Department of Human Genetics, Sri Ramachandra Institute of Higher Education and Research
Ph.D
University of Cologne, Germany 2009
M.Sc
Sri Ramachandra Institute of Higher Education and Research 2001
B,Sc
University of Madras 1999
Professor Jun 2021 – Present
Sri Ramachandra Institute of Higher Education and Research | Department of Human Genetics

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Scholarly Work

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Scholarly Publications

Abstract\# 1920: CGP049090 and PKF115-584 selectively induce apoptosis of CLL cells in vitro and in vivo by inhibition of beta-catenin/lef-1 signaling.

Open Access
misc
Year: 2009.
Authors: Gandhirajan, Rajesh and Gehrke, Iris and Plickert, G\ 'unter and Schl\ 'osser, Axel and Schmitt, Elisabeth and Hallek, Michael and Kreuzer, Karl-Anton

Disruption of CTNNB1/LEF-1 Complex by Small Molecule Inhibitors Induces Apoptosis in B-CLL Cells in Vitro and in Vivo

Open Access
misc
Year: 2008.
Authors: Gandhirajan, Rajesh Kumar and Gehrke, Iris and Paesler, Julian and Razavi, Regina and Filipovich, Alexandra and Erdfelder, Felix and Hertweck, Magdalena and Plickert, Guenter and Schmitt, Esther Katharina and Schlösser, Axel and others

The Para-Isomer of Nitric Oxide-Donating Acetylic Salicylic Acid (p-NO-ASA) Effectively Induces Cell Death in B-Cell Chronic Lymphocytic Leukemia (CLL) Cells at Low Micromolar Concentrations.

Open Access
misc
Year: 2008.
Authors: Razavi, Regina and Paesler, Julian and Gehrke, Iris and Erdfelder, Felix and Hertweck, Magdalena and Filipovich, Alexandra and Gandhirajan, Rajesh Kumar and Hallek, Michael and Kreuzer, Karl Anton

Chronic Lymphocytic Leukemia (CLL) Cells Require Microenvironmental Stimuli to Resist Apoptosis through Activation of STAT3 Mediated by VEGF.

Open Access
article
Year: 2008. Volume: 112 , Pages: 1069 .
Authors: Gehrke, Iris and Paesler, Julian and Gandhirajan, Rajesh Kumar and Razavi, Regina and Filipovich, Alexandra and Erdfelder, Felix and Hertweck, Magdalena and Hallek, Michael and Kreuzer, Karl Anton

Inhibition of WNT/LEF1 signaling by small molecule inhibitors promotes rapid apoptosis in chronic lymphocytic leukemia (CLL)

Open Access
misc
Year: 2008.
Authors: Gandhirajan, Rajesh and Gehrke, Iris and Plickert, Guenter and Staib, Peter and Schlosser, Axel and Schmitt, Esther and Hallek, Michael and Kreuzer, Karl-Anton

Selective killing of B cell chronic lymphocytic leukemia (B-CLL) cells through specific inhibition of beta-catenin/lef-1 signaling by two small molecule compounds (CGP049090 and PKF115-584)

Open Access
misc
Year: 2007.
Authors: Gandhirajan, Rajesh Kumar and Staib, Peter and Hempsch, Birgit and Minke, Katharina and Gehrke, Iris and Schinkothe, Timo and Plickert, Guenter and Schlosser, Axel and Schmitt, Esther and Hallek, Michael and others

Clinical Plasma Medicine

Open Access
article
Year: 0000.
Authors: Pasqual-Melo, Gabriella and Gandhirajan, Rajesh Kumar and Stoffels, Ingo and Bekeschus Sander