Ministry of Education
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Prof Rajesh Kumar Gandhirajan

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Male

Professor, Department of Human Genetics
Sri Ramachandra Institute of Higher Education and Research

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Expertise

  • Biology

Publications

Total Articles 71
Books 0
Proceedings 0

Publications

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Scopus

Citations 2013
h-index 24

CrossRef

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Citations 1779
h-index 23
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SOCIETY FOR REDOX BIOLOGY AND MEDICINE

2021
Life

Bio

Biochemist, Hands on experience in drug screening, high content imaging, phenologic analysis, high throughput gene expression analysis and target validation in vitro and in vivo

Personal Details

  • Male
  • Professor , Sri Ramachandra Institute of Higher Education and Research
  • Department of Human Genetics, Sri Ramachandra Institute of Higher Education and Research
Ph.D
University of Cologne, Germany 2009
M.Sc
Sri Ramachandra Institute of Higher Education and Research 2001
B,Sc
University of Madras 1999
Professor Jun 2021 – Present
Sri Ramachandra Institute of Higher Education and Research | Department of Human Genetics

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Scholarly Work

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Scholarly Publications

Potent Antineoplastic Activity of Two Inhibitors of Lymphoid Enhancer Binding Factor-1 (LEF-1) in Chronic Lymphocytic Leukemia (B-CLL).

Open Access
article
Year: 2009. Volume: 114 , Pages: 885 .
Authors: Gandhirajan, Rajesh Kumar and Gehrke, Iris and Filipovich, Alexandra and Paesler, Julian and Razavi, Regina and Erdfelder, Felix and Hertweck, Magdalena and Poll-Wolbeck, Simon Jonas and Uhrmacher, Sabrina and Schl\ 'osser, Axel and others

Lack of WNT Pathway Co-Receptors as a Possible Reason for Chronic Lymphoctic Leukemia (CLL) Cells Resistance to Dickkopf-1 (DKK1).

Open Access
misc
Year: 2009.
Authors: Filipovich, Alexandra and Gandhirajan, Rajesh Kumar and Gehrke, Iris and Paesler, Julian and Poll-Wolbeck, Simon Jonas and Uhrmacher, Sabrina and Hertweck, Magdalena and Erdfelder, Felix and Razavi, Regina and Hallek, Michael and others

INDUCTION OF APOPTOSIS IN CHRONIC LYMPHOCYTIC LEUCEMIA CELLS BY THE PARA-ISOMER OF NITRIC OXIDE-DONATING ACETYLSALICYLIC ACID (P-NO-ASA) AT LOW MICROMOLAR CONCENTRATIONS

Open Access
inproceedings
Year: 2009. Volume: 94 , Pages: 307--308 .
Authors: Razavi, R and Gehrke, I and Gandhirajan, RK and Paesler, J and Filipovich, A and Erdfelder, F and Hertweck, M and Uhrmacher, S and Hallek, M and Kreuzer, KA

INHIBITION OF LEF-1 EFFECTIVELY INDUCES APOPTOSIS IN CHRONIC LYMPHOCYTIC LEUKEMIA IN VITRO AND IN VIVO

Open Access
inproceedings
Year: 2009. Volume: 94 , Pages: 199--199 .
Authors: Gandhirajan, RK and Gehrke, I and Plickert, G and Schloesser, A and Schmitt, EK and Hallek, M and Kreuzer, KA

The Para-Isomer of Nitric Oxide Donating Acetylsalicylic Acid (p-NO-ASA) Induces Apoptosis in Chronic Lymphocytic Leukemia (CLL) in Vitro and In Vivo without Gross Systemic Toxicities.

Open Access
article
Year: 2009. Volume: 114 , Pages: 3783 .
Authors: Razavi, Regina and Gehrke, Iris and Gandhirajan, Rajesh Kumar and Poll-Wolbeck, Simon Jonas and Paesler, Julian and Erdfelder, Felix and Hertweck, Magdalena and Filipovich, Alexandra and Uhrmacher, Sabrina and Hallek, Michael and others

Evidence for a Pathological Ratio of CD44s/CD44v6 in Chronic Lymphoctic Leukemia (CLL) Cells.

Open Access
misc
Year: 2009.
Authors: Hertweck, Magdalena and Erdfelder, Felix and Filipovich, Alexandra and Uhrmacher, Sabrina and Gandhirajan, Rajesh Kumar and Gehrke, Iris and Paesler, Julian and Razavi, Regina and Poll-Wolbeck, Simon Jonas and Hallek, Michael and others

VASCULAR ENDOTHELIAL GROWTH FACTOR ACTS VIA AUTO-AND PARACRINE MECHANISMS AS A CRITICAL MICROENVIRONMENTAL FACTOR FOR THE SURVIVAL OF CHRONIC LYMPHOCYTIC LEUKEMIA CELLS

Open Access
inproceedings
Year: 2009. Volume: 94 , Pages: 136--137 .
Authors: Gehrke, I and Paesler, J and Gandhirajan, RK and Razavi, R and Hallek, M and Kreuzer, K-A

Abstract\# 3452: VEGF promotes CLL cell survival via a dual mechanism, upregulation of the oncogene STAT3 and downregulation of the tumor suppressors RB1 and E2F1

Open Access
misc
Year: 2009.
Authors: Gehrke, Iris and Paesler, Julian and Gandhirajan, Rajesh and Razavi, Regina and Hallek, Michael and Kreuzer, Karl-Anton