Prof Purnananda Guptasarma
vidwan id: 89467
Professor, Department of Biological Sciences
Indian Institute of Science Education and Research(IISER), Mohali
Expertise
- Biology
Publications
Publications
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Scopus
h-index
19
CrossRef
Citations
1025
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15
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Professional Recognition
AVRA YOUNG SCIENTIST AWARD
AV Rama Rao Foundation, HyderabadCSIR YOUNG SCIENTIST AWARD
Council of Scientific and Industrial Research (CSIR)A.K. BOSE MEMORIAL MEDAL
Indian National Science Academy, New DelhiINSA MEDAL FOR YOUNG SCIENTISTS
Indian National Science Academy, New DelhiTATA Transformation Prize (Sustainability)
TATA Sons and New York Academy of SciencesMember
Guha Research Conference, IndiaYoung Associate
Indian Academy of Sciences, BangaloreCommunity & Membership
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New York Academy of Sciences
Indian Biophysical Society
Indian Biophysical Society
Bio
I am a structural biochemist, molecular biophysicist, molecular biologist and cell biologist. My research interests focus upon the science, design and engineering of proteins, and protein-related or protein-derived technologies. I work with (or have worked with) questions relating to protein design and redesign relating to issues of folding; misfolding and aggregation; thermodynamic and kinetic stability; enzymatic activity and/or other function; interactions of proteins with other molecules.
Personal Details
- Male
- Professor , Indian Institute of Science Education and Research(IISER), Mohali
- IISER Mohali
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Co-Authors (13)
National Institute of Pharmaceutical Education and Research (NIPER), Mohali
Indian Institute of Science Education and Research(IISER), Mohali
Amity University
Indian Institute of Technology Delhi
Post Graduate Institute of Medical Sciences
CSIR-Institute of Microbial Technology
Indian Institute of Technology Ropar
N/A
Indian Institute of Science Education and Research(IISER), Mohali
Indian Institute of Science Education and Research(IISER), Mohali
Indian Institute of Science Education and Research(IISER), Mohali
CSIR-Institute of Microbial Technology
DAV University
Scholarly Work
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Towards understanding and manipulating the aggregation of globular proteins
Folding and stability of sequence-recombined proteins: Effects of backbone reversal and secondary structure shuffling
Structural-biochemical studies of the mechanisms of folding and kinetic stabilization of proteins from hyperthermophiles
Structural-biochemical studies of protein (mis)folding and aggregation
Probind subtle facets of the sequence-structure relationship: Folding and stability studies of sequence-redesigned proteins
Folding and stability of hyperthermophile proteins
Short-circuiting natural evolution through selected transplantations of residues to engineer the physical behavior of protein surfaces
Kinetically stable macromolecules: Studies of extremophile proteins and a protein aggregate
Examination and modulation of the aggregation of some disease-related proteins
Exploration of the extreme structural stability of Pyrococcus furiosus rubredoxin
Engineering of beta sheet-based and beta alpha barrel protein structures
Studies on selected biomolecules and their roles in cell proliferation, cytotoxicity and disease
Folding, stability and DNA binding of E. coli HU and its engineered variants
BsuAP, an aminopeptidase from Bacillus subtilis: Structural-biochemical and mutational exploration of function
Studies of the structural-biochemical behavior of individual (and combined) extracellular domains of human E- and N-cadherins
Structural-biochemical and mechanistic studies of two novel and versatile archaeal glucanotransferase-cum-exoamylase enzymes
Role of the bacterial nucleoid associated protein, HU, in cell-cell and cell-DNA interactions through the binding of HU with eDNA and lipopolysaccharide
Engineering the degradation of polyethylene terephthalate (PET) through synergistic action of diverse thermostable enzymes
Biophysical and photochemical studies of nucleoid associated proteins with special emphasis on HU and Dps
Mechanistic and functional enzymology of a hyperthermophilic starch hydrolase-glucanotransferase and a mesophilic aminopeptidase
Studies of cohesin-dockerin interactions and linker sequences in the enzymatic components of cellulosomes from Clostridium thermocellum
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