Ministry of Education
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Dr Basant Kumar Patel

vidwan id: 62174
Male

Associate Professor, Department of Biotechnology
Indian Institute of Technology Hyderabad

Orchid Icon 0000-0001-9465-4803 Google Scholar Icon 56998136300 Researcher Icon Y-8732-2019 Google Scholar Icon Boh2iMkAAAAJ

Expertise

  • Biotechnology and Applied Microbiology

Publications

Total Articles 40
Books 0
Proceedings 0

Publications

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Scopus

Citations 1304
h-index 15

CrossRef

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Citations 1266
h-index 14
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Community & Membership

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Bio

Protein Misfolding, Human Amyloidoses and Prion Diseases, Yeast as a Model Eukaryote for Amyloid Formation and Toxicity

Personal Details

  • Male
  • Associate Professor , Indian Institute of Technology Hyderabad
  • Indian Institute of Technology Hyderabad, Kandi
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Associate Professor May 2010 – Present
Indian Institute of Technology Hyderabad | Department of Biotechnology

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Co-Authors (5)

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Dr Anamika Bhargava

Indian Institute of Technology Hyderabad

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Dr Rajakumara Eerappa

Indian Institute of Technology Hyderabad

Himanshu

Dr Himanshu Joshi

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Scholarly Work

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Scholarly Publications

Therapeutic targeting of the oxidative stress generated by pathological molecular pathways in the neurodegenerative diseases, ALS and Huntington's

Open Access
Review
European Journal of Pharmacology. Year: 2025. Volume: 987 .
Authors: Bajpai A.;Bharathi V.;Patel B.K.
DOI 10.1016/j.ejphar.2024.177187
3

Activation of the yeast MAP kinase, Slt2, protects against TDP-43 and TDP-25 toxicity in the Saccharomyces cerevisiae proteinopathy model

Open Access
Article
Biochemical and Biophysical Research Communications. Year: 2024. Volume: 741 .
Authors: Bajpai A.;Bharathi V.;Kumawat R.;Tomar R.S.;Patel B.K.
DOI 10.1016/j.bbrc.2024.151062

Computational Insights Into the Mechanism of EGCG's Binding and Inhibition of the TDP-43 Aggregation

Open Access
Article
Year: 2024. Volume: 104 , Issue: 4 .
Authors: Meshram V.;Balaji R.;Saravanan P.;Subbamanda Y.;Deeksha W.;Bajpai A.;Joshi H.;Bhargava A.;Patel B.
DOI 10.1111/cbdd.14640

In silicoandin vitrostudies suggest epigallocatechin gallate (EGCG), a polyphenol in green tea, can bind and modulate the aggregation and cytotoxicity of the full-length TDP-43 protein implicated in TDP-43 proteinopathies

Open Access
preprint
Year: 2023.
Authors:
DOI 10.1101/2023.12.22.573011
1

TDP-43 proteinopathy mechanisms from non-mammalian model systems

Open Access
Book Chapter
Year: 2022. Pages: 153-181 .
Authors: Bharathi V.;Girdhar A.;Patel B.K.
DOI 10.1016/B978-0-12-820066-7.00002-3
1 1

In Vitro Interaction of a C-Terminal Fragment of TDP-43 Protein with Human Serum Albumin Modulates Its Aggregation

Open Access
Article
Year: 2022. Volume: 126 , Issue: 45 , Pages: 9137-9151 .
Authors: Nirwal S.;Saravanan P.;Bajpai A.;Meshram V.D.;Raju G.;Deeksha W.;Prabusankar G.;Patel B.K.
DOI 10.1021/acs.jpcb.2c04469
5 4

Elevated constitutive expression of Hsp40 chaperone Sis1 reduces TDP-43 aggregation-induced oxidative stress in Ire1 pathway dependent-manner in yeast TDP-43 proteinopathy model of amyotrophic lateral sclerosis

Open Access
Article
Biochemical and Biophysical Research Communications. Year: 2022. Volume: 595 , Pages: 28-34 .
Authors: Bharathi V.;Bajpai A.;Parappuram I.T.;Patel B.K.
DOI 10.1016/j.bbrc.2022.01.073
10 11

Zn2+ modulates in vitro phase separation of TDP-432C and mutant TDP-432C-A315T C-terminal fragments of TDP-43 protein implicated in ALS and FTLD-TDP diseases

Open Access
Article
International Journal of Biological Macromolecules. Year: 2021. Volume: 176 , Pages: 186-200 .
Authors: Preethi S.;Bharathi V.;Patel B.K.
DOI 10.1016/j.ijbiomac.2021.02.054
8 8