Ministry of Education
Vidvan Image

Dr Saptarshi Sinha

vidwan id: 341959
Male

,

Orchid Icon 0000-0003-0687-924X Google Scholar Icon 57161829900 Researcher Icon GSI-4567-2022 Google Scholar Icon GqhNusQAAAAJ

Expertise

  • Oncology

Publications

Total Articles 29
Books 0
Proceedings 0

Publications

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Scopus

Citations 477
h-index 14

CrossRef

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Citations 218
h-index 10
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Professional Recognition

2023

Research Excellence Award

Institute of Scholars (InSc), under Ministry of MSME & Corporate Affairs, Govt. of India
2022

Best Oral Presentation

Indian Association of Biomedical Scientists
2019

Senior Research Fellowship

Indian Council of Medical Research

Community & Membership

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International Association of Oncology

2021
Student Member

American Association for Cancer Research

2020
Associate Member

Manipal-Government of Karnataka Bioincubator

2020
Life Member

Indian Association of Cancer Research

2019
Life Member

New Zealand Association of Breast Cancer Research

2019
Member

Bio

I am a highly motivated, hard-working, and responsible biomedical researcher aiming to conduct cancer research and develop novel and improved anti-cancer therapeutics. During my doctoral research at KIIT University, I worked on the development of a chemotherapeutic regimen to target breast cancer cells by inducing DNA damage and simultaneously inhibiting the DNA repair pathways. I used in vitro, ex vivo and in vivo pre-clinical model systems to address my research questions.

Personal Details

  • Male
  • KIIT Deemed to be University
Ph.D.
KIIT Deemed to be University, Bhubaneswar 2024
Postgraduate Diploma in Science
Other Institute 2016
Master of Science
Bangalore University 2013
Bachelor of Science
Bangalore University 2009
Research Scholar Jul 2020 – Sep 2024
KIIT Deemed to be University, Bhubaneswar | School of Biotechnology
Senior Research Fellow Jul 2019 – Jul 2022
KIIT Deemed to be University, Bhubaneswar | School of Biotechnology
Project Assistant Sep 2018 – Mar 2019
KIIT Deemed to be University, Bhubaneswar | School of Biotechnology

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Co-Authors (4)

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Scholarly Work

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Scholarly Publications

Quinacrine inhibits cMET-mediated metastasis and angiogenesis in breast cancer stem cells

Open Access
Article
Journal of Cell Communication and Signaling. Year: 2023. Volume: 17 , Issue: 4 , Pages: 1371-1388 .
Authors: Das B.;Sethy C.;Chatterjee S.;Dash S.R.;Sinha S.;Paul S.;Goutam K.;Kundu C.N.
DOI 10.1007/s12079-023-00756-9
3 7

Red Wine Polyphenol Resveratrol Reduces Breast Cancer Progression and PARP Inhibitor Olaparib Efficiently Enhances its Anti-cancer Action

Open Access
editorial
Year: 2023. Volume: 7 , Pages: 1 .
Authors: Sinha S, Kundu CN

Veliparib (ABT-888), a PARP inhibitor potentiates the cytotoxic activity of 5-fluorouracil by inhibiting MMR pathway through deregulation of MSH6 in colorectal cancer stem cells

Open Access
Article
Expert Opinion on Therapeutic Targets. Year: 2023. Volume: 27 , Issue: 10 , Pages: 999-1015 .
Authors: Paul S.;Chatterjee S.;Sinha S.;Dash S.R.;Pradhan R.;Das B.;Goutam K.;Kundu C.N.
DOI 10.1080/14728222.2023.2266572
1 11

Talazoparib enhances the quinacrine-mediated apoptosis in patient-derived oral mucosa CSCs by inhibiting BER pathway through the modulation of GCN5 and P300

Open Access
Article
Medical Oncology. Year: 2023. Volume: 40 , Issue: 12 .
Authors: Das C.;Dash S.R.;Sinha S.;Paul S.;Das B.;Bhal S.;Sethy C.;Kundu C.N.
DOI 10.1007/s12032-023-02222-3
1 8

Combination of talazoparib and olaparib enhanced the curcumin-mediated apoptosis in oral cancer cells by PARP-1 trapping

Open Access
Article
Journal of Cancer Research and Clinical Oncology. Year: 2022. Volume: 148 , Issue: 12 , Pages: 3521-3535 .
Authors: Chatterjee S.;Dhal A.K.;Paul S.;Sinha S.;Das B.;Dash S.R.;Kundu C.N.
DOI 10.1007/s00432-022-04269-7
10 18

Targeting cancer stem cells in the tumor microenvironment: An emerging role of PARP inhibitors

Open Access
Review
Pharmacological Research. Year: 2022. Volume: 184 .
Authors: Paul S.;Sinha S.;Kundu C.N.
DOI 10.1016/j.phrs.2022.106425
10 16

Olaparib enhances the Resveratrol-mediated apoptosis in breast cancer cells by inhibiting the homologous recombination repair pathway

Open Access
Article
Experimental Cell Research. Year: 2022. Volume: 420 , Issue: 1 .
Authors: Sinha S.;Chatterjee S.;Paul S.;Das B.;Dash S.R.;Das C.;Kundu C.N.
DOI 10.1016/j.yexcr.2022.113338
11 19

NIR irradiation enhances the apoptotic potentiality of quinacrine-gold hybrid nanoparticles by modulation of HSP-70 in oral cancer stem cells

Open Access
Article
Year: 2022. Volume: 40 .
Authors: Dash S.R.;Chatterjee S.;Sinha S.;Das B.;Paul S.;Pradhan R.;Sethy C.;Panda R.;Tripathy J.;Kundu C.N.
DOI 10.1016/j.nano.2021.102502
10 17