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Dr Moneesha Fernandes

vidwan id: 275559

Female

Senior Principal Scientist, Organic Chemistry
CSIR National Chemical Laboratory

0000-0002-0751-3541 Google Scholar Icon

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46062069600

Expertise

Organic Chemistry

Publications

Total Articles 41

Books 0

Proceedings 0

Publications

Scopus

Citations 179

h-index 8

CrossRef

Citations 216

h-index 9

Google Scholar

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Professional Recognition

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Community & Membership

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Chemical Research Society of India (CRSI)

LIfe Member

Indian Peptide Society (IPS)

Life Member

Bio

Organic and Biomolecular Chemistry of Nucleic Acids, Peptides and Analogues

Personal Details

Female
Senior Principal Scientist , CSIR National Chemical Laboratory
CSIR-National Chemical Laboratory, Dr Homi Bhabha Rd, Ward No. 8, NCL Colony, Pashan

Ph.D.

Other Institute 2001

Senior Principal Scientist Jan 2002 – Present

CSIR National Chemical Laboratory | Organic Chemistry

Related Profiles

Experts (2814+)

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Dr Rakesh Sharma L

Vice Principal

Research Scholar

Assistant Professor

Mr Ravisinh Solanki

Assistant Professor

Ms Krupa Badava

Assistant Professor

Mr S. Shiva Kumar

Research Fellow

Ms Sonali Joshi

Assistant Professor

Dr M Vishnu Devan

Associate Professor

Dr Mydhili S. P.

Assistant Professor

Mr Pranav Avhad

Assistant Professor

Organisations (121+)

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Dr Bhushan Chaudhari

Senior Principal Scientist

Dr Senthilkumar Beeran

Principal Scientist

Dr Benudhar Punji

Principal Scientist

Dr Santhakumari B

Senior Principal Scientist

Dr Ashootosh Ambade

Principal Scientist

Principal Scientist

Dr Avishek Saha

Scientist

Senior Scientist

Scientist

Senior Principal Scientist

Co-Authors (13)

CSIR National Chemical Laboratory

Dr Dhiman Sarkar

CSIR National Chemical Laboratory

Dr Durba Sengupta

CSIR National Chemical Laboratory

Dr Deenan Santhiya

Delhi Technological University

Dr Kiran Kulkarni

CSIR National Chemical Laboratory

Dr Santosh Kumar

National Institute of Technology Rourkela

Dr Muthukumarasamy Karthikeyan

CSIR National Chemical Laboratory

Dr Munia Ganguli

CSIR-Institute of Genomics and Integrative Biology

Dr Mahesh Kulkarni

CSIR National Chemical Laboratory

Dr Rajesh Gonnade

CSIR National Chemical Laboratory

Dr Rakesh Joshi

CSIR National Chemical Laboratory

Dr Sarika Mehra

Indian Institute of Technology Bombay

Dr Souvik Maiti

CSIR-Institute of Genomics and Integrative Biology

Scholarly Work

Process Development for Nusinersen: An Orphan Drug Used to Treat Spinal Muscular Atrophy (SMA)

Funding Agency: Department of Science and Technology, Govt. of India

PI

13,970,060

2023 - Ongoing

Ongoing

Design and development of Indigenous Strain Portfolio for the production of Penicillin (PenV-IP)

Funding Agency: CSIR

Member

0

2021 - 2023

Completed

Phyto-inspired peptides derived from plant protease inhibitor for crop protection

Funding Agency: CSIR

Member

0

2020 - 2023

Completed

Development of process for active pharmaceutical ingredients towards COVID-19 (COVID-API)

Funding Agency: CSIR

Member

0

2020 - 2021

Completed

Processes & Technologies for Crop Protection Chemicals

Funding Agency: CSIR

Member

0

2019 - 2020

Completed

Characterization and comparison of vaccine antigens and cultures

Funding Agency: Industry

CO-PI

0

2017 - 2018

Completed

Investigating the effect of disulfide depletion on therapeutic peptides

Funding Agency: Department of Science and Technology, Govt. of India

PI, Mentor

2,300,000

2017 - 2020

Completed

IsoDNA/isoRNA G-quadruplex oligomers for increased stability and biological function competence

Funding Agency: SERB

PI

2,718,000

2015 - 2018

Completed

Genome Dynamics in Cellular Organization, Differentiation and Enantiostasis (GenCODE

Funding Agency: CSIR

PI

0

2012 - 2017

Completed

Towards Understanding Skin Cell Homeostasis (TOUCH)

Funding Agency: CSIR

PI

0

2012 - 2017

Completed

Screening Molecules in Lead Exploration (SMILE)

Funding Agency: CSIR

Co-PI

0

2012 - 2017

Completed

'Development of a Novel, Sensitive, Versatile and Simple-to-use Fluorescence-based Strand-invasion Assay

Funding Agency: Inhouse

PI

250,000

2007 - 2008

Completed

Design and Synthesis of Novel Conformationally Constrained Cell Penetrating Peptides for Efficient Cellular Uptake’

Funding Agency: CSIR

Co-PI

0

2007 - 2012

Completed

Arginine-rich Tat- and (R-X-R)-motif Peptidomimetics for DNA/RNA Binding, Antimicrobial Action and Cell Penetration

University AcSIR (CSIR-NCL)

Year 2018

Design and Synthesis of Peptidomimetics, Cellular Delivery Systems and Bioconjugates

University Academy of Scientific and Innovative Research ((AcSIR))

Year 2018

Alkyl proline and oxytocin derivatives towards development of anti-diabetics and design of potential antifolates derived from guanine

University Academy of Scientific and Innovative Research ((AcSIR))

Year 2022

IsoDNA/isoRNA oligomers of the thrombin binding aptamer and 2’- thiopropyl and abasic ethanediol substitutions therein

University Academy of Scientific and Innovative Research ((AcSIR))

Year 2022

Effect of 3’-fluoro substitution and loop modification in 2’-phosphodiester-linked thrombin-binding aptamer (TBA) on its structure and function

University Academy of Scientific and Innovative Research ((AcSIR))

Year 2020

G-rich iso-RNA oligomers as aptamers

Vaijayanti A. Kumar

Moneesha Fernandes

Atish A. Wagh

- Patent No. : US 2023/0212586 A1 Filed : 21-12-2022

Published : 06-07-2023 Published

A phenylcarbonate derivative, process for preparation and use thereof

Moneesha Fernandes

Amit Kumar Yadav

- Application No. : 201811014118 Filed : 13-04-2018

Published : 18-10-2018 Published

A phenylcarbonate derivative, process for preparation and use thereof

Moneesha Fernandes

Amit Kumar Yadav

- Application No. : 201811014118 Filed : 13-04-2018

Published : 18-10-2018 Published

Method for identifying and quantifying carboxyethyl valine modified haemoglobin

Mahesh Jagdishrao Kulkarni

Jagadeeshaprasad Guddarangaiah Mashanipalya

Kedar Balaji Batkulwar

Moneesha Fernandes

- Patent No. : US 2017/0074888 A1 Filed : 01-09-2016

Published : 16-03-2017 Published

G-rich isoDNA sequences forming G-quadruplex structure, their function as aptamers and a process for the preparation thereof

Vaijayanti A. Kumar

Anita D. Gunjal

Moneesha Fernandes

- Patent No. : US 9914928 B2 Filed : 23-05-2014

Published : 13-03-2018 Published

Locked and unlocked 2'-O-phosphoramidite nucleosides, process of preparation thereof and oligomers comprising the nucleosides

Vaijayanti A. Kumar

Anita D. Gunjal

Moneesha D'Costa

Namrata D. Erande

Venubabu Kotikam

- Patent No. : US 2011/0196141 A1 Filed : 07-09-2010

Published : 11-08-2011 Published

Chiral, Charged Peptide Nucleic Acid Oligomers from Cyclic Monomers-I

V. A. Kumar

Moneesha D’Costa and K. N. Ganesh

- Patent No. : US 7,479,536 B1 Filed : 20-09-2000

Published : 20-01-2009 Published

Scholarly Publications

Implications of Natural 3'-5'- Linkages in the Loop Region of Isomeric 2'-5'-Linked Thrombin-Binding Aptamer

article

CHEMISTRYSELECT. Year: 2024. Volume: 9 , Pages: e202304254 .

Authors: Manisha Aher, Vaijayanti A. Kumar, Moneesha Fernandes

DOI

10.1002/slct.202304254

Discovery of Free Glycated Amines and Glycated Urea in Diabetic Plasma: Potential Implications in Diabetes

article

ACS Omega. Year: 2024. Volume: 9 , Pages: 24907-24915 .

Authors: Shaikh, Rashdajabeen; Das, Sancharini; Chaurasiya, Arvindkumar; Ashtamy, Murali; Sheikh, Amreen; Fernandes, Moneesha; Tiwari, Shalbha; Unnikrishnan, Ambika; Kulkarni, Mahesh

Unlike RNA-TBA (rTBA), iso-rTBA, the 2'-5'-linked RNA-thrombin-binding aptamer, is a functional equivalent of TBA

article

Year: 2023. Volume: 59 , Pages: 1461-1464 .

Authors: Atish A. Wagh, Vaijayanti A. Kumar, Sapna Ravindranathan, Moneesha Fernandes

Replacement of Loop Residues in TBA by an Abasic Ethylene Glycol Spacer: Effect on Stability, Structure and Function

article

CHEMISTRYSELECT. Year: 2021. Volume: 6 , Pages: 10648-10650 .

Authors: Atish A. Wagh, Monika Ghalawat, Moneesha Fernandes

PNA-mediated efflux inhibition as a therapeutic strategy towards overcoming drug resistance in Mycobacterium smegmatis

Article

Microbial Pathogenesis. Year: 2021. Volume: 151 .

Authors: Ghosh S.;Cotta K.B.;Hande A.A.;Fernandes M.;Mehra S.

DOI

10.1016/j.micpath.2021.104737

3

3

Influence of fluorine substitution on the molecular conformation of 3′-deoxy-3′-fluoro-5-methyluridine

Article

Year: 2020. Volume: 76 , Pages: 346-352 .

Authors: Aher M.N.;Erande N.D.;Kumar V.A.;Fernandes M.;Gonnade R.G.

DOI

10.1107/S2053229620003083

1

Methoxymethyl Threofuranosyl Thymidine (4′-MOM-TNA-T) at the T7 Position of the Thrombin-Binding Aptamer Boosts Anticoagulation Activity, Thermal Stability, and Nuclease Resistance

Article

ACS Omega. Year: 2020. Volume: 5 , Issue: 1 , Pages: 498-506 .

Authors: Varada M.;Aher M.;Erande N.;Kumar V.A.;Fernandes M.

DOI

10.1021/acsomega.9b03042

10

7

2′-5′-Isomerically Linked Thrombin-Binding Aptamer (isoTBA) Forms a Stable Unimolecular Parallel G-Quadruplex in the Presence of Sr<sup>2+</sup> Ions

Article

CHEMISTRYSELECT. Year: 2019. Volume: 4 , Issue: 36 , Pages: 10668-10673 .

Authors: Wagh A.;Fernandes M.

DOI

10.1002/slct.201902005

1

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