Ministry of Education
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Dr Udit Chaube

vidwan id: 194728
Male

Assistant Professor, Department of Pharmacy
Institute of Pharmacy, Nirma University

Orchid Icon 0000-0002-3130-7510 Google Scholar Icon 57031762500 Researcher Icon AAA-9489-2021 Google Scholar Icon 2KwGuRsAAAAJ

Expertise

  • Medicine Research and Experimental

Publications

Total Articles 17
Books 0
Proceedings 0

Publications

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Scopus

Citations 157
h-index 7

CrossRef

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Citations 13
h-index 1
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Professional Recognition

2014

SCHOLESTIC GOLD MEDAL

NIRMA UNIVERSITY
2014

DST INSPIRE FELLOWSHIP

DEPARTMENT OF SCIENCE & TECHNOLOGY
2023

International Travel Grant

ICMR

Community & Membership

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INDIAN SOCIETY FOR TECHNICAL EDUCATION

2023
life-time

Bio

Cancer biology, Design and Synthesis of Novel Leads as mTOR inhibitors and CDK2 inhibitors, Molecular modelling and Computer Aided Drug Design

Personal Details

  • Male
  • Assistant Professor , Institute of Pharmacy, Nirma University
  • Nirma University S.G. Highway
Ph.D.
Other Institute 2019
Assistant Professor Dec 2021 – Present
Institute of Pharmacy, Nirma University | Department of Pharmacy

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Co-Authors (7)

Bhumika

Dr Bhumika Patel

Institute of Pharmacy, Nirma University

Bhoomika

Dr Bhoomika Patel

National Forensic Sciences University

Hardik

Dr Hardik Bhatt

Institute of Pharmacy, Nirma University

Inderbhan

Mr Inderbhan Singh

National Forensic Sciences University

Gopal

Prof Gopal Natesan

Institute of Pharmacy, Nirma University

Rakesh

Prof Rakesh Rawal

Gujarat Biotechnology University

Vivek

Dr Vivek Vyas

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Scholarly Work

Targeting mTOR: Design, Synthesis and biological Evaluation of Novel Anticancer Agents for the Mitigation of Lung Cancer

Funding Agency: Nirma University

PI

200,000

2024 - Ongoing

Ongoing
Identification of Tetrahydroquinoline (THQ) derivatives as novel mTOR inhibitor with highly improved anticancer activity.

Funding Agency: Nirma University

PI

100,000

2022 - 2023

Completed
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Scholarly Publications

Tetrahydroquinoline: an efficient scaffold as mTOR inhibitor for the treatment of lung cancer

Open Access
Review
Future Medicinal Chemistry. Year: 2022. Volume: 14 , Issue: 23 , Pages: 1789-1809 .
Authors: Chaube U.;Dey R.;Shaw S.;Patel B.D.;Bhatt H.G.
DOI 10.4155/fmc-2022-0204
6

Identification of potent, non-toxic, selective CDK2 inhibitor through the pharmacophore-based scaffold hopping, molecular dynamics simulation-assisted molecular docking study, Lee Richard contour map analysis, and ADMET properties

Open Access
Article
Year: 2022. Volume: 33 , Issue: 6 , Pages: 1895-1905 .
Authors: Chaube U.;Bhatt H.
DOI 10.1007/s11224-022-01958-4
1

Design and development of Tetrahydro-Quinoline derivatives as dual mTOR-C1/C2 inhibitors for the treatment of lung cancer

Open Access
Article
Year: 2021. Volume: 106 .
Authors: Chaube U.J.;Rawal R.;Jha A.B.;Variya B.;Bhatt H.G.
DOI 10.1016/j.bioorg.2020.104501
13 14

CoMFA, CoMSIA, Topomer CoMFA, HQSAR, molecular docking and molecular dynamics simulations study of triazine morpholino derivatives as mTOR inhibitors for the treatment of breast cancer

Open Access
Article
Computational Biology and Chemistry. Year: 2019. Volume: 80 , Pages: 351-363 .
Authors: Chhatbar D.M.;Chaube U.J.;Vyas V.K.;Bhatt H.G.
DOI 10.1016/j.compbiolchem.2019.04.017
34

Beneficial Effect of Silymarin in Pressure Overload Induced Experimental Cardiac Hypertrophy

Open Access
Article
Cardiovascular Toxicology. Year: 2019. Volume: 19 , Issue: 1 , Pages: 23-35 .
Authors: Sharma B.;Chaube U.;Patel B.M.
DOI 10.1007/s12012-018-9470-2
13

3D-QSAR, molecular dynamics simulations, and molecular docking studies on pyridoaminotropanes and tetrahydroquinazoline as mTOR inhibitors

Open Access
Article
Molecular Diversity. Year: 2017. Volume: 21 , Issue: 3 , Pages: 741-759 .
Authors: Chaube U.;Bhatt H.
DOI 10.1007/s11030-017-9752-9
18

Design and synthesis of potent N-phenylpyrimidine derivatives for the treatment of skin cancer

Open Access
Article
RSC Advances. Year: 2016. Volume: 6 , Issue: 13 , Pages: 10285-10297 .
Authors: Chaube U.;Vyas V.;Bhatt H.
DOI 10.1039/c5ra27017k
10

3D-QSAR, molecular dynamics simulations and molecular docking studies of benzoxazepine moiety as mTOR inhibitor for the treatment of lung cancer

Open Access
Article
Year: 2016. Volume: 26 , Issue: 3 , Pages: 864-874 .
Authors: Chaube U.;Chhatbar D.;Bhatt H.
DOI 10.1016/j.bmcl.2015.12.075
43