Expertise

  • Medicinal Chemistry

Publications

Total Articles 39
Books 0
Proceedings 0

Publications

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Scopus

Citations 151
h-index 6

CrossRef

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Citations 79
h-index 4
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Professional Recognition

2015

Postdoctoral Fellowship (2015-2018)

The Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-Fiocruz fellowship by the Go
2001

Junior Research Fellowship

All India Council for Technical Education (AICTE)
2003

Silver Jubilee Fund Award

Government College of Pharmacy, Bengaluru, Karnataka
2020

STARS Award 2020 for Teachers for ‘Excellence in Academic Research’

American Association of Government College of Pharmacy (Bengaluru) Alumni, New York, USA

Community & Membership

Atal Ranking of Institution on Innovation Achievements (ARIIA) of Acharya & BM Reddy Colle

Nodal Officer
2019

Institution Innovation Council of Acharya & BM Reddy College of Pharmacy, Bengaluru

Member Secretary

Scientific and Industrial Research Organization of Gokaraju Rangaraju Educational Society,

In-Charge

Indian Pharmaceutical Association

2007
Life Member

Indian Society for Technical Education

2007
Life Member

Association of Pharmaceutical Teachers of India

2006
Life Member

Karnataka State Pharmacy Council

1999
Registered Pharmacist

Bio

Integrated approaches of drug discovery including computer-aided drug design, medicinal chemistry, and cell biological approaches targeting HSP90, BRAF Kinase, COX-2 and TLR proteins for the treatment of cancer and inflammatory diseases.

Personal Details

  • Male
  • Hesarghatta Main Road, Jalahalli West, Bengaluru, Karnataka, India
Ph.D
Other Institute 2008
M. Pharm
Other Institute 2003
B. Pharm
Bangalore University 1999
Professor Jul 2018 – May 2025
Acharya B M Reddy College of Pharmacy | pharmaceutical chemistry
Post-Doctoral Fellow Sep 2012 – Oct 2013
Purdue University
Professor Jul 2008 – Jun 2015
Gokaraju Rangaraju College of Pharmacy | Pharmaceutical Chemistry
Senior Lecturer Feb 2003 – Jun 2008
Acharya B M Reddy College of Pharmacy | pharmaceutical chemistry

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Scholarly Work

Discovery of triangular heterocyclic molecules as inhibitors of dual oncogenic pathways triggered by HSP90 and BRAF kinase

Funding Agency: Indian Council of Medical Research (ICMR)

Principal Investigator

30,25,028.00

2020 - Ongoing

Ongoing
Discovery of trigonal heterocyclic molecules as oncogenic BRAF inhibitors for the treatment of small cell lung carcinoma

Funding Agency: All India Council for Technical Education (AICTE)

Principal Investigator

15,27,451.00

2020 - Ongoing

Ongoing
Molecular design, chemical synthesis and anticancer studies of tri-substituted heterocyclic compounds as HSP90 inhibitors

Funding Agency: Rajiv Gandhi University of Health Sciences (RGUHS)

Principal Investigator

7,00,000.00

2020 - Ongoing

Ongoing
Effects of mearnsitrin on doxorubicin induced apoptosis in H9C2 cells

Funding Agency: Rajiv Gandhi University of Health Sciences (RGUHS)

Co- Investigator

3,00,000.00

2019 - Ongoing

Ongoing
Chemical synthesis of novel nicotine analogs

Funding Agency: Advance Product Research, LLC, New Jersey, USA

Principal Investigator

18,41,355.00

2016 - 2017

Completed
To study the disruption of oncogenic HSP90-Client protein interactomes to treat cancer

Funding Agency: Dept. of Health Research (DHR)

Principal Investigator

25,38,922.00

2015 - 2017

Completed
Unveiling the novel drugs targeting RAF-MEK-ERK signaling cascade for anti-cancer therapy

Funding Agency: Department of Science and Technology, Govt. of India

Mentor

24,31,000.00

2015 - 2018

Completed
HSP90 chemical and structural proteomics for oncogenic protein target discovery

Funding Agency: Indian Council of Medical Research (ICMR)

Post doctoral Fellow

21,29,760.00

2012 - 2013

Completed
Design and development of Ras/Raf interaction inhibitors

Funding Agency: All India Council for Technical Education (AICTE)

Principal Investigator

17,79,000.00

2010 - 2012

Completed
Design and development of HSP90 inhibitors

Funding Agency: Department of Science and Technology, Govt. of India

Principal Investigator

14,76,000.00

2010 - 2013

Completed
Tools for the design and synthesis of drugs

Funding Agency: All India Council for Technical Education (AICTE)

Coordinator

1,00,000.00

2010 - 2010

Completed

Phytochemical and pharmacological studies of Guazuma ulmifolia

University Jawaharlal Nehru Technological University
Year 2017

Phytochemical and pharmacological evaluation of herbal products for metabolic syndrome

University Jawaharlal Nehru Technological University
Year 2017

Docking, SAR studies, synthesis & biological evaluation of novel HSP90 inhibitors

University Osmania University
Year 2019
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Scholarly Publications

Synthesis of novel HSP90 inhibitor for breast cancer and human melanoma.

Open Access
conference proceedings
Authors: Shashikant P, Nikhila P, Sundeep K, Raghavendra NM

Rational identification of hsp90 inhibitors as anticancer lead molecules by structure based drug designing approach

Open Access
ARTICLE
Authors: Gupta, S.D. and Swapanthi, P.S. and Bhagya, D. and Federicci, F. and Mazaira, G.I. and Galigniana, M.D. and Subrahmanyam, C.V.S. and Gowrishankar, N.L. and Raghavendra, N.M.

Development of novel S PC-3 gefitinib lipid nanoparticles for effective drug delivery in breast cancer. Tissue distribution studies and cell cytotoxicity analysis

Open Access
ARTICLE
Authors: Nayek, S. and Raghavendra, N.M. and Sajeev Kumar, B.

Discovery of N-pyridoyl-Δ2-pyrazolines as Hsp90 inhibitors

Open Access
ARTICLE
Authors: Kadasi, S. and Yerroju, R. and Gaddam, S. and Pullanagiri, N. and Chary, M. and Pingili, D. and Raj, S. and Raghavendra, N.M.

Conserved water molecule-dependent docking strategy and atom-based 3D QSAR studies to design heat shock protein 90 inhibitors

Open Access
ARTICLE
Authors: Gupta, S.D. and Subrahmanyam, C.V.S. and Gowrishankar, N.L. and Raghavendra, N.M.

Natural heat shock protein 90 inhibitors in cancer and inflammation

Open Access
ARTICLE

Dual or multi-targeting inhibitors: The next generation anticancer agents

Open Access
ARTICLE
Authors: Raghavendra, N.M. and Pingili, D. and Kadasi, S. and Mettu, A. and Prasad, S.V.U.M.

Drug design, synthesis and in vitro evaluation of substituted benzofurans as hsp90 inhibitors

Open Access
ARTICLE
Authors: Kadasi, S. and Costa, T.E.M.M. and Arukala, N. and Toshakani, M. and Duggineti, C. and Thota, S. and Gupta, S.D. and Raj, S. and Penido, C. and Henriques, M.G. and Raghavendra, N.M.